Artemeth20mg+Lumefan120mg tabs/24/PAC-30

General Description:
Artemether 20mg + Lumefantrine 120mg fixed dose combination tablets, strip of 24 tablets/pack of 30

Technical specifications:
Each tablet contains Artemether 20mg Ph.Int. and Lumefantrine 120mg

Therapeutic class:
Artemether is an Artemesinin derivative
Lumefantrine is a synthetic racemic fluorene mixture

Standard shelf life:
2 years (24 months)

Other available formulations:
The product may also be available in other formulations or pack sizes.

Indications:
Treatment of acute uncomplicated malaria caused by P. falciparum alone or with other Plasmodium spp. in areas with significant drug resistance; by Mouth (PO)

Dosage:
Suggested dosing is based on the WHO guidelines for the treatment of Malaria, see link listed below:

href="http://www.who.int/malaria/publications/atoz/9241546948/en/index.h tml" target="blank">WHO guidelines for the treatment of Malaria"


Storage:
Do not store above 30 degrees Celsius (86 degrees Fahrenheit);
Store in tightly closed original container;
Keep out of the reach and sight of children.

Dispensing instructions:
Lumefantrine absorption is enhanced by co-administration with fat. Patients with acute malaria are often averse to food, therefore, they should be encouraged to resume intake as soon as they can tolerate food to improve absorption. Patients or carers should be advised of the need to take Artemether and Lumefrantine with milk or fat-containing food, particularly on the second (2nd) and third (3rd) day of treatment.

Patients should be advised to repeat dose if vomiting occurs within one hour of taking the last dose.

Guidelines for use:
For more details, please see the links listed below:

Guidelines for the treatment of Malaria


WHO Model List of Essential Medicines


WHO Model Formulary


or your regional/national guidelines.

Regulatory Status:
For latest updates, please click the links listed below:

List of WHO Prequalified Medicines


List of USFDA approved and tentatively approved items