Td vaccine for adults,vial of 10 doses

General Description:
Td vaccine for adults, adsorbed, vial of 10 doses

The vaccine contains purified tetanus and diphtheria toxoids, with a reduced dose of the diphtheria component. One dose of 0.5ml has a potency of 4.0 International Units of diphtheria toxoid, and 40 International Units of tetanus toxoids. The toxoids are adsorbed onto Aluminum Phosphate. Thiomersal is used as a preservative. This vaccine is used for the active immunization of adults and children 7 years of age and older against diphtheria and tetanus.

For information on product specifications, refer to the WHO website on Prequalified Vaccines.
https://www.who.int/immunization_standards /vaccine_quality/PQ_vaccine_list_en/en/

Administration:
The vaccine should be shaken before use to homogenize the suspension. It should be injected intramuscularly in the upper arm. A sterile syringe and needle should be used for each injection.

Once opened, multi-dose vials should be kept between +2°C and +8°C. Multi-dose vials of Td from which one or more doses of vaccine have been removed during an immunization session may be used in subsequent immunization sessions for up to a maximum of 4 weeks, provided that all of the following conditions are met (as described in the WHO policy statement: The use of opened multi-dose vials in subsequent immunization sessions. WHO/V&B/00.09):

The expiry date has not passed.
The vaccines are stored under appropriate cold chain conditions.
The vaccine vial septum has not been submerged in water
Aseptic technique has been used to withdraw all doses.
The vaccine vial monitor (VVM), if attached, has not reached the discard point.

Immunization Schedule:
Td vaccine may be used as a primary immunization for persons from 7 years of age. They should receive two doses of 0.5ml of adsorbed Td with reduced dose of diphtheria for adults at an interval of at least four weeks. A third dose is recommended at least 6 months after the second dose. It may be given at the same time as measles, polio (OPV and IPV), hepatitis B, haemophilus influenzae type b, and yellow fever vaccines and vitamin A supplementation ("Adsorbed DT for children" is recommended for children aged less than 7 years). Even if that situation of giving Td with BCG never occurs, there is nothing IN the vaccine that would prevent it from being given with BCG.

After a primary immunization course of either DTP or Td, adsorbed Td for adults may be used as a booster at intervals of approximately 10 years, but with a minimum of at least one year between doses. It can safely replace monovalent tetanus toxoid (TT) vaccine, including during pregnancy.

Transport and Storage:
Td should be protected from light and stored and transported between +2°C and +8°C. The vaccine must not be frozen.