Measles vaccine, vial of 5 doses

General Description:
Measles vaccine, vial of 5 doses

It is an attenuated live virus vaccine.
This vaccine is a freeze-dried product that must be reconstituted only with the sterile diluents provided separately for that purpose. The virus strain contained in the vaccine can differ depending on the manufacturer.

The strains which are currently pre-qualified by the WHO are: Edmonston Zagreb, Schwarz and Biken Cam 70 for measles.

For information on product specifications, refer to the WHO website on

https://www.who.int/immunization_standards /vaccine_quality/PQ_vaccine_list_en/en/

Administration:
Immunization consists of a single dose of 0.5ml injected percutaneously(subcutaneous or intra-muscular), preferably in the upper arm. A sterile needle and sterile syringe must be used for each injection. Because of sensitivity to ultraviolet light, avoid exposing the vaccine to sunlight. Once the vaccine has been reconstituted, it should be used the same day (preferably immediately but by no means beyond six (6) hours after reconstitution), and only then if the vial has been maintained between +2°C and +8°C and protected from sunlight. Any opened container remaining at the end of a session (within six hours of
reconstitution) should be discarded. The vaccine vial monitor, if present, would have been removed on reconstitution.

The diluent supplied is specially designed for use with this vaccine. Only this diluent may be used to reconstitute the vaccine. Do not use diluents from other types of vaccine or for measles vaccine from other manufacturers. Water for injection may not be used for this purpose. Using an incorrect diluent may result in damage to the vaccine and/or serious reactions to those receiving the vaccine. Diluent must not be frozen but must be cooled between +2°C and +8°C before reconstitution.

Immunization Schedule:
In countries where the incidence and mortality from measles is high in the first year of life, the recommended age for immunization against measles is at 9 months of age (270 days) or shortly after. In countries where infection occurs later in life (due to sustained high vaccine coverage), the age of immunization can be moved to 12-15 months. A second opportunity is needed both to increase the chance that every
child receives at least one dose of measles vaccine and to increase the proportion of the population that is fully immunized. The second dose can be given at least one month after the first dose through routine or supplemental activities. Measles vaccine can be given safely and effectively simultaneously with DTP, Td, TT, BCG, polio (OPV and IPV), haemophilus influenzae type b, hepatitis B, and yellow fever vaccines and vitamin A supplementation.

Precondition for utilisation:
For vaccination campaign and routine immunization activities. The number of vaccines will depend on the number of children to be immunized.

Complementary requirements to be ordered separately:
AD syringes and Reconstitution syringes, cold chain (ice packs, vaccine carriers, thermometers, freezers, generators).

Emergency scenarios
Preventable (Measles) outbreak, vaccination campaigns

Transport and storage:
Freeze-dried measles vaccine should be kept in the refrigerator between +2°C and +8°C until used; it can also be kept in minus condition up to -20C. The vials of vaccine and the diluent should be transported together, but the diluent must not be frozen. The vaccine should be protected from sunlight and/or ultra UV.

Context in which item is mainly used:
Reinforce national system/structures, refugee camps, emergency response to natural disaster

Target population:
Measles vaccine to be administered by healthcare workers to children less than 15 years old.