PCV, 10-val., 4 dose vial

For more information on the price of this product, refer to PCV Vaccine Prices

General Description:
pneumococcal CONJUGATE VACCINE, 10-VALENT 4 dose vial

Technical specifications:
Synflorix (pneumococcal polysacharide conjugate vaccine (adsorbed)) is a sterile suspension for injection. One dose (0.5 ml) contains 1 microgram of polysaccharide for serotypes 1, 5, 6B, 7F, 9V, 14 and 23F, and 3 micrograms of polysaccharide for serotypes 4, 18c and 19F. Synflorix is manufactured as a liquid preparation. After shaking, the vaccine is a homogenous, white suspension.

Synflorix 4-dose vial contains the preservative 2-Phenoxyethanol

COMPOSITION Paediatric Dose
Volume per dose0.5mL
Pneumococcal polysaccharide for serotypes
1, 5, 6B, 7F, 9V, 14, & 23F 7ug
Pneumococcal polysaccharide for serotype 4, 18C, 19F 3ug
Adsorbed on aluminum phosphate (adjuvant) 0.5mg
Conjugated to carrier protein D (derived from non-typeable H. influenzae) 9-16ug
3 conjugated to tetanus toxoid carrier protein 5-10ug
4 conjugated to diphtheria toxoid carrier protein 3-6ug

Excipients: sodium chloride,
2-phenoxyethanol 5mg
Water for injection

Shelf life:
36 months

Storage and transportation:
Transport and store refrigerated at +2ºC to +8ºC.
DO NOT FREEZE. Discard if the vaccine has been frozen.
Once opened, multi-dose vials should be kept between +2°C and +8°C. Multi-dose vials from which one or more doses of vaccine have been removed during an immunisation session may be used in subsequent immunization sessions for up to a maximum of 28 days provided that all of the following conditions are met:
The expiry date has not passed.
The vaccines are stored under appropriate cold chain conditions.
The vaccine vial septum has not been submerged in water.
Aseptic technique has been used to withdraw all doses.
The vaccine vial monitor (VVM), if attached, has not reached the discard point (see Figure 1).

Vaccine Vial Monitors (VVMs) have been applied to the vial label on all Synflorix 4dose Vials manufactured by GSK. The colour dot which appears on the vial label is the VVM. This is a time-temperature sensitive dot that provides an indication of the cumulative heat to which the vial has been exposed. It warns the end user when exposure to heat is likely to have degraded the vaccine beyond an acceptable level.
The interpretation of the VVM is simple. Focus on the central square. Its colour will change progressively. As long as the colour of this square is lighter than the colour of the ring, then the vaccine can be used. As soon as the colour of the central square is the same colour as the ring or of a darker colour than the ring, then the vial should be discarded.


Packaging and labeling:
PRESENTATION: Vial, containing 4 x 0.5 ml Doses (25 or 50 vials per package